Opportunity Information: Apply for SFOP0009242
The CTR Global Biosecurity Engagement Activities opportunity (Funding Opportunity Number SFOP0009242) is a U.S. Department of State, Bureau of International Security and Nonproliferation (ISN) funding announcement issued through the Office of Cooperative Threat Reduction (CTR). It is funded under the Nonproliferation, Anti-terrorism, Demining and Related Programs (NADR) account and is structured as a discretionary cooperative agreement, meaning awardees should expect substantial involvement, coordination, or oversight from the U.S. government during implementation rather than operating entirely independently. The program sits within CTRs broader mission set of reducing threats posed by weapons of mass destruction, their delivery systems, and advanced conventional weapons risks associated with both state and non-state proliferators.
The specific line of effort covered by this notice is the Biosecurity Engagement Program (BEP). BEPs core national security objective is to reduce global biological threats by limiting the ability of proliferator states, terrorist groups, and other malicious actors to obtain or misuse the ingredients needed for a biological weapons capability. In practical terms, the notice emphasizes three main risk areas: access to specialized biological expertise, access to dangerous biological materials (including high consequence pathogens, agents and toxins on control lists such as the U.S. Select Agent List, and synthetic biological materials), and access to dual-use equipment that could be repurposed for harmful biological work. The underlying logic is that modern life sciences can be used for legitimate public health and research, but some of the same knowledge, materials, and tools can be redirected toward biological weapons development or biological attacks if safeguards and norms are weak.
A consistent theme across CTR and ISN programming, and explicitly stated in this opportunity, is long-term sustainability. The program is not designed to create permanent dependence on U.S. funding or outside technical support. Instead, projects are expected to build durable local capacity, policies, systems, and partnerships that continue to function after the award ends. This usually implies an emphasis on institutional strengthening, responsible oversight of pathogens and sensitive research, improving biosecurity and biosafety practices, and establishing or reinforcing governance and risk management approaches that partner countries and institutions can maintain over time.
From an administrative standpoint, the opportunity was created on October 31, 2022, with an original application closing date of January 31, 2023. The award ceiling is listed as $500,000, and the agency anticipated making about 30 awards, suggesting a portfolio approach that spreads funding across multiple implementers and activities rather than concentrating resources into a small number of large projects. The CFDA number associated with the opportunity is 19.033. Eligibility is listed broadly as "Others," indicating that applicants beyond standard categories may be considered, but the notice signals that the details are clarified elsewhere in the full eligibility section.
Overall, this funding opportunity is aimed at practical, implementable projects that help prevent the misuse of dangerous pathogens, sensitive biological materials, and dual-use tools, while reinforcing international biosecurity in ways that protect the United States, its allies, and U.S. interests abroad. The cooperative agreement structure and the focus on sustainability imply that strong proposals would typically demonstrate clear threat-reduction outcomes, measurable and enduring capacity gains for foreign partners, and a realistic plan for coordination with U.S. government stakeholders throughout the project lifecycle.Apply for SFOP0009242
- The Department of State, Bureau of International Security-Nonproliferation in the other (see text field entitled explanation of other category of funding activity for clarification) sector is offering a public funding opportunity titled "CTR Global Biosecurity Engagement Activities" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 19.033.
- This funding opportunity was created on Oct 31, 2022.
- Applicants must submit their applications by Jan 31, 2023. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 30 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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